2871-2873
| (2E)-5-[3-[(Phenylsulfonyl)amino]phenyl]- pent-2-en-4-ynohydroxamic Acid and Its Derivatives as Novel and Potent Inhibitors of ras Transformation
Mitsuaki Ohtani,
Takaharu Matsuura,
Kazuhiro Shirahase, and
Kenji Sugita
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2874-2876
| (S)-(+)-2-(3'-Carboxybicyclo[1.1.1]pentyl)- glycine, a Structurally New Group I Metabotropic Glutamate Receptor Antagonist
Roberto Pellicciari,
Mariarosa Raimondo,
Maura Marinozzi,
Benedetto Natalini,
Gabriele Costantino, and
Christian Thomsen
[Full Article -
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2877-2886
| Conformational Studies and Electronic Structures of Tamoxifen and Toremifene and Their Allylic Carbocations Proposed as Reactive Intermediates Leading to DNA Adduct Formation
Hiroshi Kuramochi
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2887-2893
| The Properties of Known Drugs. 1. Molecular Frameworks
Guy W. Bemis and
Mark A. Murcko
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2894-2899
| Inhibition of UDP-N-Acetylglucosamine Import into Golgi Membranes by Nucleoside Monophosphates
Andrea J. Traynor,
Edina T. Hall,
Gennyne Walker,
Wayne H. Miller,
Paul Melançon, and
Robert D. Kuchta
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2900-2906
| Structure-Activity Relationships of the Antimalarial Agent Artemisinin. 4. Effect of Substitution at C-3
Mitchell A. Avery,
Sanjiv Mehrotra,
Jason D. Bonk,
Jeffrey A. Vroman,
D. Keith Goins, and
Robert Miller
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2907-2914
| N-Heteroaryl-2-phenyl-3-(benzyloxy)piperidines: A Novel Class of Potent Orally Active Human NK1 Antagonists
T. Ladduwahetty,
R. Baker,
M. A. Cascieri,
M. S. Chambers,
K. Haworth,
L. E. Keown,
D. E. MacIntyre,
J. M. Metzger,
S. Owen,
W. Rycroft,
S. Sadowski,
E. M. Seward,
S. L. Shepheard,
C. J. Swain,
F. D. Tattersall,
A. P. Watt,
D. W. Williamson, and
R. J. Hargreaves
[Full Article -
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2915-2921
| Synthesis and Binding Activity of Some Pyrazolo[1,5-c]quinazolines as Tools To Verify an Optional Binding Site of a Benzodiazepine Receptor Ligand
Vittoria Colotta,
Daniela Catarzi,
Flavia Varano,
Guido Filacchioni, and
Lucia Cecchi
, Alessandro Galli and
Chiara Costagli
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2922-2938
| Cardiovascular Characterization of Pyrrolo[2,1-d][1,5]benzothiazepine Derivatives Binding Selectively to the Peripheral-Type Benzodiazepine Receptor (PBR): From Dual PBR Affinity and Calcium Antagonist Activity to Novel and Selective Calcium Entry Blockers
Giuseppe Campiani,
Isabella Fiorini,
Maria P. De Filippis,
Silvia M. Ciani,
Antonio Garofalo,
Vito Nacci,
Gianluca Giorgi,
Alessandro Sega,
Maurizio Botta,
Alberto Chiarini,
Roberta Budriesi,
Giancarlo Bruni,
Maria R. Romeo,
Cristina Manzoni, and
Tiziana Mennini
[Full Article -
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2939-2952
| Similarities and Differences in the Structure-Activity Relationships of Capsaicin and Resiniferatoxin Analogues
Christopher S. J. Walpole,
Stuart Bevan,
Graham Bloomfield,
Robin Breckenridge,
Iain F. James,
Timothy Ritchie,
Arpad Szallasi,
Janet Winter, and
Roger Wrigglesworth
[Full Article -
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2953-2961
| Dihydrobenzofuran Analogues of Hallucinogens. 3. Models of 4-Substituted (2,5-Dimethoxyphenyl)alkylamine Derivatives with Rigidified Methoxy Groups
Aaron P. Monte,
Danuta Marona-Lewicka,
Matthew A. Parker,
David B. Wainscott,
David L. Nelson, and
David E. Nichols
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2962-2970
| 7-[3-(1-Piperidinyl)propoxy]chromenones as Potential Atypical Antipsychotics
Jordi Bolós,
Santiago Gubert,
Lluís Anglada,
Josep M. Planas,
Carme Burgarolas,
Josep M. Castelló,
Aurelio Sacristán, and
José A. Ortiz
[Full Article -
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2971-2979
| Synthesis and Activity of a Novel Series of 3-Biarylquinuclidine Squalene Synthase Inhibitors
George R. Brown,
David S. Clarke,
Alan J. Foubister,
Susan Freeman,
Peter J. Harrison,
Michael C. Johnson,
Keith B. Mallion,
John McCormick,
Fergus McTaggart,
Alan C. Reid,
Graham J. Smith, and
Melvyn J. Taylor
[Full Article -
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2980-2989
| Interaction of 1,4-Dihydropyridine and Pyridine Derivatives with Adenosine Receptors: Selectivity for A3 Receptors
A. Michiel van Rhee,
Ji-long Jiang,
Neli Melman,
Mark E. Olah,
Gary L. Stiles, and
Kenneth A. Jacobson
[Full Article -
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2990-3000
| Synthesis of the Four Isomers of 4-Aminopyrrolidine-2,4-dicarboxylate: Identification of a Potent, Highly Selective, and Systemically-Active Agonist for Metabotropic Glutamate Receptors Negatively Coupled to Adenylate Cyclase
James A. Monn,
Matthew J. Valli,
Bryan G. Johnson,
Craig R. Salhoff,
Rebecca A. Wright,
Trevor Howe,
Ann Bond,
David Lodge,
Larry A. Spangle,
Jonathan W. Paschal,
Jack B. Campbell,
Kelly Griffey,
Joseph P. Tizzano, and
Darryle D. Schoepp
[Full Article -
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3001-3013
| Medetomidine Analogs as  2-Adrenergic Ligands. 2. Design, Synthesis, and Biological Activity of Conformationally Restricted Naphthalene Derivatives of Medetomidine
Xiaoyan Zhang,
Xiao-Tao Yao,
James T. Dalton,
Gamal Shams,
Longping Lei,
Popat N. Patil,
Dennis R. Feller,
Fu-Lian Hsu,
Cliff George, and
Duane D. Miller
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3014-3018
| Identification of a 3-Hydroxylated Tacrine Metabolite in Rat and Man: Metabolic Profiling Implications and Pharmacology
William F. Pool,
Thomas F. Woolf,
Michael D. Reily,
Bradley W. Caprathe,
Mark R. Emmerling, and
Juan C. Jaen
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3019-3029
| Synthesis and Pharmacological Activity of Triazole Derivatives Inhibiting Eosinophilia
Youichiro Naito,
Fumihiko Akahoshi,
Shinji Takeda,
Takehiro Okada,
Masahiko Kajii,
Hiroko Nishimura,
Masanori Sugiura,
Chikara Fukaya, and
Yoshio Kagitani
[Full Article -
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3030-3034
| 3-[2-(N-Phenylacetamide)]-1,5-benzodiazepines: Orally Active, Binding Selective CCK-A Agonists
Timothy M. Willson,
Brad R. Henke,
Tanya M. Momtahen,
Peter L. Myers,
Elizabeth E. Sugg,
Rayomand J. Unwalla,
Dallas K. Croom,
Robert W. Dougherty,
Mary K. Grizzle,
Michael F. Johnson,
Kennedy L. Queen,
Thomas J. Rimele,
Jeffrey D. Yingling, and
Michael K. James
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